Down syndrome is one cause of intellectual disability among children, which can be detectable prenatally. Screening for Down syndrome on a population basis required a thorough understanding of the principles involved in the screening.
The presence or the absence of Down Syndrome is based on age, nuchal translucency, presence or absence of any physical abnormalities, and level of Fß-hCG, PAPP-A and PLGF proteins. Practically the screening has been feasible in Western countries, however, how easy or difficult is the screening of Down Syndrome in the Indian scenario?
