A 64-year-old woman was brought with complaints of crushing substernal chest pain and shortness of breath. She was previously diagnosed with colorectal cancer and was being treated with bevacizumab 5 mg/kg in combination with 5-fluorouracil every 2 weeks. On examination, her blood pressure was 181/100 mmHg with a pulse rate of 87 bpm. Cardiac examination was normal, with a regular rhythm.

However, electrocardiogram showed 2 mm anteroseptal ST elevation, indicating an ST-elevation myocardial infarction (STEMI). She was then rushed to the catheterization laboratory where she was diagnosed with an acute thrombus in the left anterior descending coronary artery. The interventional cardiologist reported the embolic nature of the thrombus (due to the absence of any ulcerated plaques) with normal coronary arteries. The lesion was treated with balloon angioplasty followed by dual antiplatelet…