A 58-year-old man with metastatic colon cancer presented to the hospital to discuss the treatment plan further. He was diagnosed seven years ago when he complained of severe and frequent abdominal pain. History: The patient is a known case of gout and hyperlipidemia. Investigations: Multiple liver and peritoneal masses were discovered during CT scan. A descending colon mass was discovered during a colonoscopy; the biopsy revealed adenocarcinoma.
Extensive RAS investigation indicates zero mutations (wild-type). Eastern Cooperative Oncology Group performance score for the patient was 1. Pharmacological management: The patient was administered FOLFIRI/cetuximab and was responding well. Due to disease progression, he was shifted to FOLFOX/bevacizumab but still experienced further progression. The patient was then administered regorafenib 160 mg once daily as a 4-week cycle (day…
