The Chikungunya virus is a mosquito-borne arbovirus especially prevalent in tropical regions and has been the cause of major epidemics in recent years. 1 Symptoms of this disease include severe arthralgia, high fever, maculopapular rash, and viremia. The current treatment options are non-specific and include antivirals and antipyretics along with anti-rheumatic drugs for patients with severe joint pains.
Since neither specific treatment nor vaccine is available for chikungunya, there is an urgent need for prophylaxis against chikungunya virus infection. Need for the study The recent uptick in the number of cases of chikungunya infections, particularly in lower-to-middle-income countries, has further warranted the need for effective prophylaxis against this disease. A study published in The Lancet in June 2023 entitled, Safety and Immunogenicity of a Single-shot Live-attenuated…
