A cardiorenal syndrome is the deterioration of renal function accelerated by worsening of heart failure. Although it is a frequent clinical entity due to the improved survival of heart failure patients, its pathophysiology is still not well understood. Thus a therapeutic approach for its management is important. This article outlines some therapeutic options for management of cardiorenal syndrome .
Worsening heart failure or acute decompensated heart failure (ADHF) can accelerate worsening of renal function - called cardiorenal syndrome (CRS). Recognized therapeutic strategies like diuretics and inotropes are often associated with resistance and limited clinical success. Initial clinical trials have shown promising results in some heart failure subpopulations but have failed to demonstrate a clear beneficial role of these agents. On the other hand, ultrafiltration appears to be a more…
