More recently, ASD has been used to treat a variety of ocular surface diseases, including dry eyes and dry eye-related disorders and many others. Owing to its widespread use the current article focusses on the guidelines described by the royal college of ophthalmologists on the use of serum eye drops for the management of various severe ocular surface diseases. The recommendations stated in the guideline are as follows: Serum eye drops should be considered in the following patients: Patients with refractory or partially responsive acute or chronic severe ocular surface disease.

Patients with other ocular surface conditions such as recurrent corneal erosions, persistent epithelial defects and limbal epithelial stem cell failure if licensed interventions have been unsuccessful in them. Patients undergoing ocular surface reconstruction. Clinical Situations where Autologous versus…