Tumour lysis syndrome (TLS) is a potentially deadly complication of tumours or their treatment. This syndrome consists of a constellation of laboratory findings such as hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia, known as laboratory TLS. This article provides you with an overview of Tumor lysis syndrome.
Tumour lysis syndrome (TLS) is an oncologic emergency caused by massive cell lysis of the tumour in which the release of large amounts of potassium, phosphate, and nucleic acids into the systemic circulation occurs. When clinical complications such as seizures, acute renal failure, and cardiac dysrhythmias occur in patients with laboratory TLS, the syndrome is called clinical TLS.TLS is especially common in patients with haematological malignancies with rapid cellular turnover rates such as acute lymphocytic leukaemia but is very rare in patients with solid…
