It is evident that Type 1 diabetes mellitus (T1DM) is associated with impaired bone quality and increased fracture rates. Moreover, in a recent retrospective study, it is identified that young adults with T1DM and comorbid celiac diseases are more likely to sustain fractures than those who have T1DM alone (12.2% vs. 3.5%; P = .02).
A comparable relationship between celiac disease and fracture (OR = 3.5; 95% CI, 1.01-12.12) after adjusting for age, sex, BMI, vitamin D status, hypoglycemia, microvascular complications and HbA1c, Furthermore, patients with T1DM and celiac disease were reported with higher rates of hypoglycemia, defined as at least two episodes per week, compared with those who had T1DM alone (55.1% vs. 37.7%; P < .001). As hypoglycemia is a risk factor for falls, seizures, and fractures, clinicians should actively screen for and manage hypoglycemia in patients with…
