Case presentation A 46-year-old woman with no prior psychiatric, neurological, or significant medical history presented to a psychiatry clinic accompanied by her sister for assessment of newly developed delusional misidentification. According to her sister, the patient had undergone a sudden behavioral change over the preceding two weeks, marked by emotional withdrawal, escalating anxiety, and a firm belief that her husband and 14-year-old daughter had been replaced by impostors who were physically identical but emotionally unfamiliar.

The patient described the experience as “like waking up and realizing the people I love most aren’t real anymore.” These symptoms emerged shortly after she discovered her husband’s extramarital relationship and his decision to seek divorce following over twenty years of marriage, an event she described as “the most devastating moment of my life.” She…