A 35-year-old physician presents to your clinic with a 3-day history of a cough, right-sided pleuritic chest pain, and fever. He is a non-smoker and has no allergies. His vital signs are as follows: Respiratory rate- 18 breaths/min Heart rate- 82 beats/min Oxygen saturation by pulse oximetry- 94% while breathing room air Chest radiography shows a dense right lower lobe consolidative infiltrate.

A sputum culture done at his hospital workplace on the day his symptoms began yielded the following information on Streptococcus pneumoniae susceptibility (minimum inhibitory concentration [MIC]): Penicillin- 1 μg/mL Ceftriaxone- <0.5 μg/mL Vancomycin- 0.5 μg/mL Erythromycin- >1 μg/mL Levofloxacin- <0.5 μg/mL. Source: Clinical Pearls in Infectious Diseases