Patient Case A 54-year-old male presented to the emergency department of a local hospital with a recent onset of total body rash. He had a fever and left shoulder pain for 2 days. He reported that he consumed flurbiprofen (NSAID) and a combination of acetaminophen (300 mg)/codeine (30 mg) without any prescription. On examination, the ER physician noted that the patient’s pulse rate was 76/min, with a blood pressure of 115/75 mmHg, and a temperature of 35.80C.
The physician also observed the presence of a diffuse confluent erythematous rash on the patient’s body, face, and arms. Without any investigation, he diagnosed the patient with an allergic drug reaction and prescribed prednisone, 50 mg daily for 3 days, and diphenhydramine, 50 mg every 6 hours for 7 days. On the following morning, the patient returned to the same emergency department with worsening symptoms of fever, chills,…
