Case presentation A 75-year-old woman visited a Dermatologist with recurrent episodes of angioedema since age 66. Over the years, the angioedema progressively increased in severity and frequency. She had a history of mild hypertension and was on angiotensin-converting-enzyme inhibitors (ACEI). Her family physician hypothesized that the angioedema resulted from taking ACEI, which he asked her to discontinue. However, even after discontinuation of ACEI, she had recurrent angioedema attacks for the next six years.
Her previous consultations with many other specialists failed to provide a clear diagnosis and treatment. History of presenting illness She reported that the attacks occurred over weeks or months, usually lasting for 48-72 hours. The duration of attacks was irrespective of treatment with corticosteroids and antihistamines. During the previous year, before her presentation to the…
