Researchers, including one of Indian origin have found that long-term antibiotic treatment in mice decreases levels of amyloid plaques, a hallmark of Alzheimer's disease. The study, published in the journal Scientific Reports, also showed significant changes in the gut microbiome after antibiotic treatment, suggesting the composition and diversity of bacteria in the gut play an important role in regulating immune system activity that impacts progression of Alzheimer's disease.
"We're exploring very new territory in how the gut influences brain health," said the senior author of the study and a Professor of Neurosciences at the University of Chicago. Two of the key features of Alzheimer's disease are the development of amyloidosis, accumulation of amyloid-beta peptides in the brain, and inflammation of the microglia, brain cells that perform immune system functions in the central nervous…
