A 3-year-old girl was admitted to the hospital with persistent fever for five days, generalized rash, conjunctivitis, labial and lingual erythema, and swollen feet. Physical examination Highly irritable Hemoglobin, WBC, platelets – Normal C-reactive protein - 14 mg/dL Transaminases - AST 168 U/L, ALT 86 U/L Diagnosis Based on the signs and symptoms, the patient was diagnosed with Kawasaki disease (KD). Initial treatment IVIG (2 g/kg) and aspirin (100 mg/kg) were administered. After two days Two days later, echocardiography showed mild mitral and tricuspideal regurgitation. However, there were no signs of CAA.

Electrocardiogram was normal. However, the patient did not respond to the initial IVIG treatment, and fever, rash, conjunctivitis and labial and lingual erythema remained. What should be the next step of treatment for this patient? *This case is from the Editorial Team of Docplexus…