Solve this exciting clinical case specific to your field of interest via Docplexus’ Clinical Case Challenge. Join your fellow doctors to discuss and answer today’s challenge. Case presentation: A 53-year-old woman was hospitalized with a 20-year history of wet cough and dyspnea on exertion. Bronchial asthma (BA) was diagnosed twenty years ago.
She had repeated exacerbations of BA despite being treated with high-dose inhaled corticosteroids, a long-acting β2 agonist, and a leukotriene receptor antagonist, and short-term oral corticosteroid bursts were occasionally used. Clinical investigations revealed: High levels of FeNO (53 ppb) Eosinophilia (3480/µL) and high levels of total IgE (353 IU/mL) A high-resolution CT scan of the chest revealed that both lungs had scattered centrilobular nodules and bronchial wall thickening. Patchy ground-glass opacities around the bronchioles (Cover…