Scientists have identified two new populations of cells in the brain that regulate appetite and may help develop drugs to treat obesity by controlling hunger signals."Obesity is generally associated with leptin resistance and our recent data suggest that modulation of the activity of specific neurons with drugs could bypass leptin resistance and provide a new means for reducing body weight," said the professor at Rockefeller University in the US. Researchers located the two types of cells in a part of the brainstem called the dorsal raphe nucleus.The team zeroed in on the dorsal raphe nucleus, or DRN when a whole-brain imaging revealed that this part of the brain becomes activated in hungry mice.
Subsequent imaging of other mice that were fed more than their normal amount of food, until they were full, revealed a different pattern of DRN activity.These results indicated quite clearly…
