The development of the squamous cell carcinoma (SCC) requires the accumulation of multiple genetic alterations usually preceded by detectable mucosal changes, most often leukoplakias and erythroplakia. The clinical appearance of precancerous lesions and their degree of epithelium dysplasia suggests the malignancy potential . This article outlines some of the main techniques used to improve premalignant lesion diagnosis. Squamous cell carcinoma is the most common cancer of head and neck.
A significant proportion of which develops from precancerous lesions. Recent progress in the field of biological sciences has led to identify cancer biomarkers. Several techniques have been developed to improve the clinical and cytological diagnosis of oral precancerous lesions. Some of them are discussed below: Biopsy The goal of this test is to obtain entire abnormality for histopathological…