Synopsis: Perinatal mortality and morbidity are mainly due to preterm delivery. Bacterial Vaginosis is caused by excessive growth of anaerobes thereby decrease the growth of Lactobacillus which leads to an imbalance in the vaginal microbiota. Aim of this study is to evaluate whether early clindamycin treatment will help in the reduction of late miscarriages and preterm birth. This week “MED FACT” discusses a clinical trial from Journal ‘The Lancet’ , “Early clindamycin for bacterial vaginosis in pregnancy (PREMEVA): a multicentre, double-blind, randomised controlled trial”.
Authors: Damien Subtil, Gilles Brabant, Emma Tilloy, et al. Key Takeaways: Objective: To determine the effect of early clindamycin treatment to pregnant women with bacterial vaginosis infection. Study Type: A Double-Blind Randomised Controlled Trial Participants: 5630 What was the need for this study? Bacterial…
