Synopsis The Physical Function Trial (PFT) was one of the Testosterone Trials (TTrials), that aimed to assess the effect of testosterone on mobility, falls, self-reported physical function, and patient global impression-of-change (PGIC) in older men with low concentration of testosterone and walking speed less than 1·2 m/s. This week’s “MED FACT” discusses a clinical trial from The LANCET, “Effect of testosterone replacement on measures of mobility in older men with mobility limitation and low testosterone concentrations: secondary analyses of the Testosterone Trials”. Authors: Prof Shalender Bhasin et.
al. Key Takeaways Testosterone therapy improved self-reported walking ability, and 6MWT distance but did not affect falls. Objective: To observe the effect of testosterone on mobility, falls, self-reported physical function in older men Study Type: Physical Function Trial part of TTrials…
