Midazolam is underused in multiple contexts, because it is viewed as a procedural sedation agent in the category of propofol. This study suggests that it is a great agent for sedation of the agitated patient . However, its short half-life means that it should probably be coadministered with another agent, such as haloperidol 5 mg.

Even if Intravenous route is not possible than Nasal administration can be done when an intravenous needle or jugular or femoral catheter may also be placed. Agitated patients often require sedation, but effective medication still matter of study. Investigators conducted a prospective observational study in which all patients in one emergency department who required intramuscular sedation for agitation were treated with a particular agent during a 3-week period; after 15 weeks, five agents (haloperidol 5 mg, haloperidol 10 mg, ziprasidone 20 mg, olanzapine 10…