Synopsis Excess gestational weight gain (GWG) is associated with the development of gestational diabetes mellitus (GDM). Lifestyle trials have not achieved much GWG limitation, and have largely failed to prevent GDM. The aim of the study was to compare the effect of substantial GWG limitation on maternal GDM risk. This week’s “MED FACT” discusses a randomized controlled trial from Nutrients, “Association between Gestational Weight Gain, Gestational Diabetes Risk, and Obstetric Outcomes: A Randomized Controlled Trial Post Hoc Analysis”.

Authors: Simmons et.al. Key Takeaways Lifestyle intervention in the second trimester is too late for GDM prevention, and more RCTs are needed in the first trimester. Objective: To compare the effect of substantial GWG limitations on maternal GDM risk Study Type: Randomized controlled trial Participants: 436 What Was The Need For This Study? Excess GWG is…