Synopsis Cognitive impairment and psychological comorbidity can develop in patients with Temporal Lobe Epilepsy (TLE). Although depression is common among TLE patients, its diagnosis is often ignored. Differences in glucose uptake across multiple brain regions detected with 18F-FDG PET brain imaging can help diagnose depression in TLE patients. This Journal Watch discusses the study “A PET imaging study of the brain changes of glucose metabolism in patients with temporal lobe epilepsy and depressive disorder” from BMC Medical Imaging Journal, 2021. Authors: Jin‑Feng Wen, Xin‑Wen Guo, Xiang‑Yi Cao, et al.
What was the need for this study? Temporal Lobe Epilepsy (TLE) can usually be accompanied by unique cognitive and psychiatric comorbidities. TLE originates from cortical and subcortical areas, and its symptoms often go beyond seizures. Although depressive disorder is commonly comorbid…
