Solve this exciting clinical case specific to your field of interest via Docplexus’ Clinical Case Challenge. Join your fellow doctors to discuss and answer today’s challenge. Case presentation A 13-year-old boy presented with psoriasis-like rashes and weakness of lower extremities since the age of 11 that gradually progressed to inability to ambulate independently. History The boy had rashes that developed on the scalp initially and gradually extended to the ears, armpit, back, abdomen, scrotum, and lower extremities.
Investigations A brain CT scan revealed multiple calcifications in the cerebral cortex and basal ganglia. Physical examination revealed – Diffuse psoriasiform rash with areas of pustulosis Shortness of breath with exertion Severe weakness of lower extremities (3/5 vs. 5/5 for upper extremities) Clonus upon ankle flexion The Physician's Global Assessment of Psoriasis…