A healthy 73-year-old man presented with a deformity of his left great toe that had been progressing over many years. He reported having a fasciectomy of the right hand for Dupuytren's contracture, which recurred postoperatively. He now had Dupuytren's contractures of both hands. There was no relevant family history, and he was not taking any medication.
The radiograph showed clinically significant deformity of the left first metatarsal. Histologic evaluation of the fascia showed fibromatosis characteristic of Ledderhose's disease, a rare, idiopathic proliferative disorder of the plantar aponeurosis, which may be associated with Dupuytren's contractures. What are the most probable diagnosis and treatment for this patient? *This image based case is from Docplexus editorial team for educative purpose only Source: NEJM
