Venous ulcers are only in about 1% of the adult population per year due to varicose veins or venous trauma and only form of treatment available is either Compression therapy in the form of bandage systems or hosiery or le raising up and keeping it clean and protected from infection, is the mainstay of treatment, but in trials of venous leg ulcers about half the participants remain unhealed after three months of treatment. Pentoxifylline and micronised purified flavonoid fraction are recommended adjuvants to compression, but there are barriers to use, including frequency of dosing regimen, off-label use, cost, and the quality of evidence.
Aspirin has been advocated as an adjuvant treatment for venous leg ulcers, based on suggestive evidence from two trials using 300 mg doses, although a Cochrane review concluded the evidence was insufficient to be definitive. The use of aspirin for…
