Synopsis Clinical evidence suggests that low-dose aspirin may decrease the rate of overall preterm birth. However, investigators have speculated that this is likely due to decreasing medically indicated preterm birth through its effect on the incidence of preeclampsia and other placental diseases. The present study aims to determine whether low-dose aspirin reduces the rate of spontaneous preterm birth in nulliparous women without medical comorbidities. This week’s “ MED FACT ” discusses a secondary analysis of a randomized, placebo-controlled trial from American Journal of Obstetrics & Gynecology, “ Low-dose aspirin is associated with reduced spontaneous preterm birth in nulliparous women ”. Authors: M.
Andrikopoulou, S.E. Purisch, et. al. Key Takeaways The administration of low-dose aspirin in nulliparous women without comorbidities is associated with a greater than 50% reduction in…
