Multiple Endocrine Neoplasia (MEN) is an autosomal dominant condition characterized by the combined occurrence of multiple tumors in a patient. Among the four major forms of MEN, MEN1 is estimated to affect between 1 in 50,000 and 1 in 500,000 people, while MEN2 is estimated to be prevalent in 1 in 35,000 people approximately. This article aims to provide a brief overview of MEN with an emphasis on MEN1.
What is multiple endocrine neoplasia (MEN) Occurrence of tumors in two or more endocrine glands in a single patient Previously known as Multiple Endocrine Adenopathy or the Pluriglandular Syndrome Four major forms of MEN: Types 1–4 (MEN1–MEN4). Each form manifested by the development of tumors in specific endocrine glands May be inherited as an autosomal-dominant syndrome or may occur without any known family history Table showing different types of MEN syndromes, organs affected and…
