Oncolytic viruses (OVs) have been gaining a lot of attention in recent years. OVs can be shortly described as viruses which replicate inside and kill the cancer cells without harming the normal cells in the body. Although these OVs tend to occur naturally, they can also be made in the laboratories by twitching/modifying the genetic constituents of other viruses. The research on OVs has been carried along since the nineteenth century when they were first known to the researchers.
With the development of the rodent and mice model, the search for answers of whether OVs can act as anticancer agents escalated in due course. However, the success rate in this research sector was very truncated and therefore, in 1970’s to 1980’s a majority of scientist gave up the research on OVs and moved to different fields of interest. It was only in the recent years that OVs became a topic of great interest…
