Primary sclerosing cholangitis is an idiopathic chronic progressive disorder which is characterized by inflammation, fibrosis, and narrowing of the medium and large intrahepatic and extrahepatic bile ducts. The majority of the affected patients are believed to be suffering from an ulcerative colitis which acts as a contributing factor. The disorder is associated with numerous complications such as cholestasis, cholelithiasis, cholangiocarcinoma, colon cancer, and in some progressive cases, portal hypertension.
This article gives you an overview regarding the management approach for primary sclerosing cholangitis in adults. The two major treatment goals for treating primary sclerosing cholangitis are; Reversal or the disease process Managing disease progression and its complications Management Approach Pharmacological management: There are a variety of immunosuppressive and…
