Highlights – Acid exposure on reflux monitoring predicted capacity to quit proton pump inhibitor (PPI) therapy without symptom worsening in individuals with normal reflux symptoms, poor PPI response, and no severe esophagitis. Preventing needless PPI usage and guiding tailored treatment is possible with upfront reflux monitoring without acid suppression. This Journal Watch discusses the study “Ambulatory Reflux Monitoring Guides Proton Pump Inhibitor Discontinuation in Patients with Gastroesophageal Reflux Symptoms: A Clinical Trial” from Gastroenterology Science Direct, 2021. Authors - Rena Yadlapati, Melina Masihi, C. Prakash Gyawali, Dustin A Carlson, Peter J.
Kahrilas, Billy Darren Nix, Anand Jain, Joseph R. Triggs, Michael F. Vaezi, Leila Kia, Alexander Kaizer, John E. Pandolfino What was the need for the study? Gastroesophageal reflux disease (GERD) is one of the most common…
