Renal denervation is a minimally invasive catheter-based procedure that delivers energy to the nerves in the kidneys that help regulate blood pressure. It was developed to treat resistant hypertension, which refers to high blood pressure that is not controlled by medication.
"The sham-controlled SYMPLICITY HTN-3 trial failed to show a significant blood pressure lowering effect of renal denervation," said co-principal investigator Professor, chairman, Department of Internal Medicine, University of Saarland in Homburg/Saar, Germany.2 "We applied lessons from this trial to the SPYRAL HTN-OFF MED study regarding how the procedure was performed, the patient population, and the influence of medications." SPYRAL HTN-OFF MED is an international, multicentre, prospective, randomized, sham-controlled study designed to test the safety and blood pressure lowering efficacy of treatment with the…
