The field of medicine found a new hope with a new research finding that an anticancer drug can detect hidden HIV virus. The media reported all about it in 2014. It was Romidepsin a histone deacetylase inhibitor drug found to increase virus production in HIV-infected cells 2.1 to 3.9 times than the normal. This article gives a short overview about this molecule. Romidepsin is indicated in the patients with Cutaneous T-Cell Lymphoma (CTCL) who have received at least one systemic treatment. It is naturally obtained from bacteria Chromobacterium violaceum . After getting reported in 1994, it has got FDA approval in 2009.
CTCL is a type of non-hodgkin lymphoma. It is a type of cancer of immune system. Chemically it belongs to a depsipeptide class. Pharmacological category: Histone deacetylase (HDAC) inhibitor . Mechanism of Action: Romidepsin acts as a prodrug. The reduction of the disulfide…
