Stem cells can cure type 1 Diabetes has been claimed by a biotechnology company pioneering the curative use of stem cells in regenerative medicine, today announced the achievement of pre-clinical proof-of-concept based on data from its two lead programs for type 1 diabetes testing stem cell-derived islets (SC-islets) in both non-human primates and pigs . In pre-clinical studies, SC-islets were delivered into diabetic non-human primates under immunosuppression. SC-islets were infused into the portal vein to mimic planned human clinical trials. The studies showed that: SC-islets successfully engraft and are highly functional.
Functional cells persist over six weeks in the non-human primate liver. Transplanted SC-islets reduce the requirement for insulin by more than 60 percent. Cell Therapy with Immunoprotective Device in Pigs In another pre-clinical study, pigs received SC-islets…
