There has been 9.4 million tuberculosis (TB) that could result in 1.8 million deaths. TB has become an increasingly serious global public health problem and was regarded as a major cause of illness and death. TB treatment was challenging with the emergence of multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB). However, there was still a lack of ideal and available chemotherapies for the treatment of TB.
It was urgent and valuable to develop novel anti-tuberculosis treatment (ATT) to control the global tuberculosis epidemic. Vitamin D deficiency was widespread in active tuberculosis. Vitamin D deficiency was associated with an increased susceptibility to tuberculosis infection and increased the rate of conversion from latent to active tuberculosis. Thus, vitamin D might have the capability to decrease the risk of TB infection, prevent the progression from latent…
