A drug used in the treatment of cancer may help inhibit the growth of cysts in patients with a form of inherited kidney disease, researchers have found. The findings showed that drug -- called bosutinib -- approved for the treatment of certain cases of chronic myeloid leukemia slowed cyst growth in patients with autosomal dominant polycystic kidney disease (ADPKD). This is unique reserch in the sense that first time a drug can inhibit inherited disease like this.
ADPKD is an inherited disorder that affects up to one in 1,000 people and is characterised by cysts in the kidney and other organs as liver. "The reduction in growth of cysts through treatment with bosutinib was confirmed, although gastrointestinal side effects (primarily diarrhoea), which were partly dose-dependent, may represent a substantial drawback for the further development of the drug for patients with ADPKD," said…
