ESR and CRP, two widely used inflammatory markers, can be elevated in non-rheumatologic diseases such as infections and malignancies too, making it confusing to arrive at a diagnosis in patients with nonspecific clinical presentations. ESR and CRP, two acute phase reactants, are among the most widely used inflammatory markers for the detection and follow-up of disease activity in current rheumatology practice. But, non-rheumatologic diseases such as infections and malignancies can also have similarly elevated acute phase reactants and can, therefore, be confused with the nonspecific clinical findings of rheumatic diseases (RDs).
It is very common to get false negative and false positive results on measuring the erythrocyte sedimentation rate. Most of the conditions that cannot absolutely guarantee systemic inflammation such as malignancy, can result in patients having a high erythrocyte…
