Mucosal inflammation of the nose and paranasal sinuses are the symptoms of chronic rhinosinusitis (CRS). Topical nasal sprays, oral steroids and antibiotics, and saline nasal irrigations (SNIs) are frequently used to treat CRS; however, the latter is recommended for daily use. Isotonic or hypertonic saline or seawater solutions are commonly used for SNIs, as they have been seen to directly cleanse nasal mucosa, remove antigens, biofilms or inflammatory mediators, and consequently improve mucociliary function.
1 The volume, frequency, treatment duration, and nasal devices used for SNIs vary widely. 1 In a study that assessed the effects of irrigation with sulfurous–arsenical–ferruginous thermal water versus isotonic saline solution in smokers with non-allergic CRS for 30 days, the olfactory threshold of the study participants that were treated with the isotonic saline solution was found…
