Gastric cancer is considered to be the second most common cause of cancer-related deaths worldwide. It is also reported to be the fifth most commonly diagnosed cancer, and the seventh most prevalent form of cancer in the world. However, in the last few decades, the epidemiology of gastric cancer has changed. This is possibly due to increased hygiene standards, improved nutrition, and control of Helicobacter pylori that have led to a steady decline in the incidence rate of gastric cancer.

Despite the decrease in incidence, the prognosis of gastric cancer remains poor, and the etiological factors are not adequately understood. The present article briefly reviews the critical aspects of gastric cancers, including epidemiology, classification, and etiology. The gastric mucosa is composed of columnar epithelial cells and glands that are susceptible to inflammation, peptic ulcers, and gastric…