Scientists are inventing always something unimaginable. Few years back it was very hard to detect TB until bacilli visible by AFB smear. But now researchers have developed a new blood test that can more accurately predict the development of tuberculosis (TB) up to two years before its onset in high-risk patients.

The new test predicts TB particularly in people living with persons having active TB -- a condition when the immune system is unable to stop the bacteria from growing. The blood test works by measuring the expression levels of four genes signature in the blood known as "RISK4" -- a combination of four genes associated with inflammatory responses. "We found that this prediction (up to two years before the onset of the disease) is possible through measurements of a combination of a four-gene signature in the blood," said lead author & Professor at the Stellenbosch University in…