Women, during pregnancy, are often advised to take Nonsteroidal Anti-inflammatory drugs (NSAIDs), selective cyclooxygenase (COX)-2 inhibitors or other such biological agents to relieve symptoms that may arise during the later stages of pregnancy. A recently published report has shown that NSAIDs and COX-2 inhibitors are associated with an increased risk of pre-term birth. As the average age of first-time mothers is increasing, symptoms associated with autoimmune inflammatory diseases are becoming more prevalent during pregnancy.
To manage such symptoms, clinicians often suggest the use of NSAIDs or COX-2 inhibitors to relieve symptoms like joint pain and stiffness. A population-based cohort study spanning the last two decades has, however, shown the effect of taking NSAIDs or COX-2 inhibitors in the last trimester of pregnancy. A total of 156,531 pregnancies were analyzed out of which…
