Synopsis Sjogren’s Syndrome (SS) is a systemic, chronic, autoimmune disease characterized by xerostomia (dry mouth), xerophthalmia (dry eyes) and parotid gland enlargement. Treatment options available for xerostomia include artificial saliva, topical cyclosporine, sialogogues (chewing gums, malic and ascorbic acid), and the parasympathomimetic drugs (pilocarpine and cevimeline). Several studies have demonstrated the benefits of pilocarpine for the treatment of xerostomia secondary to radiation, SS, graft-versus-host disease, and for opioid-induced oral dryness. This week’s “ MED FACT ” discusses a double-blind randomized controlled trial from British Journal of Dermatology, “ Pilocarpine and artificial saliva for the treatment of xerostomia and xerophthalmia in Sjögren syndrome: a double‐blind randomized controlled trial ”, 2018 Authors: M.
Cifuentes, P. Del Barrio‐Díaz, C. Vera‐Kellet.…
