A 60-year-old woman complained of a palpable woody feeling in her lower extremities and progressive skin tightening. Her medical history included diabetic chronic kidney disease for which she received hemodialysis, osteomyelitis, and a minor stroke six months ago for which she had to be hospitalized. Physical examination Blood pressure:120/70 mm Hg Pulse rate: 72 beats/min Woody and sclerotic appearing extremities Non-pitting swelling in both lower extremities Laboratory examination Hemoglobin: 10.5 g/dL Sodium: 140 mEq/L Potassium: 4.0 mmol/L Creatinine: 2.0 mg/dL She was on the following medications: Pioglitazone 15 mg/d orally, furosemide 60 mg/d orally, aspirin 81 mg/d orally, and darbepoetin 60 μg subcutaneously monthly.
What can be the probable diagnosis? *This case is from the Editorial team of Docplexus and is meant for educative purposes only. The correct answer will be…
