Aspirin as a strong NSAID drug is known for gastritis and other ulcers in upper GI tract but taking aspirin in combination with proton-pump inhibitors (PPIs) reduces the risk of oesophageal adenocarcinoma in patients with Barrett’s oesophagus, according to research presented at the American Society of Clinical Oncology. During the past two decades, beneficial effects from aspirin, statins, and non-steroidal anti-inflammatory drugs (NSAIDs) have been observed in epidemiological studies, initially as preventive medicine for cardiovascular disease. Protective effects have also been seen against several cancer types, including malignancies of the gastrointestinal tract.

This protection was first described for colorectal cancer and later also for oesophageal adenocarcinoma. Barrett’s oesophagus is a condition caused mainly by acid reflux, where the cells of the oesophagus grow abnormally. In…