I have a female patient 29 years old. She had right sided pleural effusion and after all investigations were diagnosed to be TB Pleural Effusion and started with the standard regimen. She improved clnically and after two weeks developed severe hepatotoxicity and ATT withdrawn. Given supportive treatment and after a week the Bil., SGOT, SGPT became normal and was kept on Inj. Streptomycin, Ethambutol 800 and Levofloxacin. After two weeks Rifampicin and isoniazid were re-introduced but with toxic signs on the 2nd day itself and now permanently withdrawn.
She is only on Inj, Streptomycin which completed two months. Now stopped. She is currently on Ethambutol 800 and Levofloxacin. What do you recommend ? Any addition ? or what is the way forward dear esteemed colleagues.