Diabetes mellitus ( DM ) is a progressively debilitating metabolic disease that results in the perturbation of carbohydrate, protein and lipid metabolism. In addition, researchers have found that more than 70% of diabetics suffer from periodontal diseases . For instance, compared to nondiabetics, incidences of dental caries are significantly higher in diabetic patients , especially in those with a poorly controlled DM.
The present article aims to evaluate the effects of diabetes on the oral microorganisms responsible for caries. Several reports have demonstrated a close association between DM and a number of oral disorders , such as xerostomia, altered taste, salivary dysfunction, dental caries, gingivitis, periodontitis, oral mucosal diseases and infections, including lichen planus, recurrent aphthous stomatitis, and candidiasis. Furthermore, occurrence of dental caries in diabetic…