Gestational diabetes mellitus (GDM) is defined as the most common pregnancy-related complication arising due to insulin resistance and hyperinsulinemia . GDM can present serious adverse outcome to the mother and baby during and after birth. Therefore, it is imperative for the mother to maintain an adequate blood glucose level throughout the entire course of pregnancy. There are several approaches to prevent GDM, among which intake of probiotics is considered to be of particular interest.
Obesity and T2DM have previously been associated with changes in the gut microbiome via inflammation, glucose and lipid metabolism. The gut microbiome has also been found to be different in pregnant women in their third trimester as compared to when they are in their first trimester. In a previous study, it has been demonstrated that supplementation with probiotics improve glycemic control in type 2…