Researchers from the US has found that a drug alone or with a combination of chemotherapy may show promising results in treating patients with blood cancer. The researchers focused on two specific proteins, directly involved in DNA repair, called histone deacetylases (HDAC) 1 and 2. The study, conducted on mice, found that the HDAC1,2 inhibitors or the HDAC1,2/doxorubicin combination, their bone marrow started turning from pale to red, indicating the white blood cells were being replaced with red blood cells.
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have discovered new science that could provide better therapeutic options for patients. Lead study author from the University of Utah said that all cancer cells containing the Philadelphia chromosome are addicted to repairing DNA. He also noted that when the drug was combined with a low…